Cargando…

Integrated serum pharmacochemistry and metabolomics reveal potential effective components and mechanisms of Shengjiang Xiexin decoction in the treatment of Clostridium difficile infection

Shengjiang Xiexin Decoction (SXD) is a widely recognized formula in Traditional Chinese Medicine (TCM) for treating diarrhea and is commonly used in clinical practice. Clostridium difficile infection (CDI) is a type of antibiotic-associated diarrhea with a rising incidence rate that has severe conse...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cui, Yutao, Zhang, Congen, Zhang, Xueqiang, Yu, Xiaohong, Ma, Yuqin, Qin, Xuemei, Ma, Zhijie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189181/ https://www.ncbi.nlm.nih.gov/pubmed/37206044 http://dx.doi.org/10.1016/j.heliyon.2023.e15602

Ejemplares similares

Preventive Effects of a Chinese Herbal Formula, Shengjiang Xiexin Decoction, on Irinotecan-Induced Delayed-Onset Diarrhea in Rats
por: Deng, Chao, et al.
Publicado: (2017)

Shengjiang Xiexin Decoction Alters Pharmacokinetics of Irinotecan by Regulating Metabolic Enzymes and Transporters: A Multi-Target Therapy for Alleviating the Gastrointestinal Toxicity
por: Guan, Huan-yu, et al.
Publicado: (2017)

Simultaneous determination of 14 active constituents of Shengjiang Xiexin decoction using ultrafast liquid chromatography coupled with electrospray ionization tandem mass spectrometry
por: Peng, Gang, et al.
Publicado: (2017)

Efficacy and safety of Shengjiang Xiexin decoction in prophylaxis of chemotherapy-related diarrhea in small cell lung cancer patients: study protocol for a multicenter randomized controlled trial
por: Deng, Chao, et al.
Publicado: (2020)

Anti-Apoptotic Role of Sanhuang Xiexin Decoction and Anisodamine in Endotoxemia
por: Liu, Zixuan, et al.
Publicado: (2021)

Pharmacokinetics and pharmacodynamics of Shengjiang decoction in rats with acute pancreatitis for protecting against multiple organ injury
por: Zhu, Lv, et al.
Publicado: (2017)

Sanhuang Xiexin decoction promotes good functional outcome in acute ischemic stroke
por: Song, Juexian, et al.
Publicado: (2018)

Serum Pharmacochemistry Analysis Using UPLC-Q-TOF/MS after Oral Administration to Rats of Shenfu Decoction
por: He, Jia-le, et al.
Publicado: (2015)

Banxia Xiexin decoction: A review on phytochemical, pharmacological, clinical and pharmacokinetic investigations
por: Zhou, Zehua, et al.
Publicado: (2023)

Investigation of Molecular Mechanism of Banxia Xiexin Decoction in Colon Cancer via Network Pharmacology and In Vivo Studies
por: Ma, Lili, et al.
Publicado: (2022)

Exploration of Gancao Xiexin decoction for treatment of Behcet disease based on network pharmacology and molecular docking
por: Zhang, Xin
Publicado: (2022)

Herbal medicine (Gancao Xiexin decoction) for Behcet disease: A systematic review protocol
por: Wu, Dongjie, et al.
Publicado: (2018)

Acute and subacute oral toxicity assessment of Gancao Xiexin decoction in Sprague-Dawley rats
por: Ru, Li, et al.
Publicado: (2023)

Modified Banxia Xiexin Decoction Ameliorates Polycystic Ovarian Syndrome With Insulin Resistance by Regulating Intestinal Microbiota
por: Zhao, Hongyu, et al.
Publicado: (2022)

Synthesis and Pharmacochemistry of New Pleiotropic Pyrrolyl Derivatives
por: Konstantinidou, Markella, et al.
Publicado: (2015)

Effectiveness of Banxia Xiexin Decoction in the treatment of precancerous lesions: A protocol for systematic review and meta-analysis
por: Yi, Ying, et al.
Publicado: (2021)

Efficacy of Banxia Xiexin decoction for chronic atrophic gastritis: A systematic review and meta-analysis
por: Cao, Yang, et al.
Publicado: (2020)

Gancao Xiexin Decoction Ameliorates Ulcerative Colitis in Mice via Modulating Gut Microbiota and Metabolites
por: Luo, Yi-ting, et al.
Publicado: (2022)

Treatment of the Gastroesophageal Reflux Disease with Chinese Herbal Medicine (BanxiaXiexin Decoction): Evidence from Meta-Analysis
por: Liu, Jiali, et al.
Publicado: (2022)

Elucidation of the Mechanisms and Molecular Targets of Sanhuang Xiexin Decoction for Type 2 Diabetes Mellitus Based on Network Pharmacology
por: Xu, Manman, et al.
Publicado: (2020)

Efficacy and Safety of Modified Banxia Xiexin Decoction (Pinellia Decoction for Draining the Heart) for Gastroesophageal Reflux Disease in Adults: A Systematic Review and Meta-Analysis
por: Dai, Yunkai, et al.
Publicado: (2017)

Banxia Xiexin Decoction in the treatment of chronic atrophic gastritis: A protocol for systematic review and meta-analysis
por: Ji, Qing, et al.
Publicado: (2020)

Combination of Active Components of Xiexin Decoction Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/Smad Pathways in db/db Diabetic Mice
por: Wu, Jia-Sheng, et al.
Publicado: (2015)

Analysis of the pharmacological mechanism of Banxia Xiexin decoction in treating depression and ulcerative colitis based on a biological network module
por: Yu, Ying, et al.
Publicado: (2020)

Targeting Clostridium difficile Surface Components to Develop Immunotherapeutic Strategies Against Clostridium difficile Infection
por: Péchiné, Séverine, et al.
Publicado: (2018)

Gancao Xiexin decoction combined with mesalazine in the treatment of ulcerative colitis: A protocol for a systematic review and meta-analysis
por: Zhong, Chun, et al.
Publicado: (2020)

Banxia Xiexin Decoction in the treatment of Hp-associated peptic ulcer: A protocol for systematic review and meta-analysis
por: Zhu, Weikai, et al.
Publicado: (2021)

Efficacy and safety of Banxia Xiexin Decoction as a complementary treatment for gastric cancer: A protocol for systematic review and meta-analysis
por: Zhang, Meiqing, et al.
Publicado: (2021)

Serum Pharmacochemistry Combined with Network Pharmacology-Based Mechanism Prediction and Pharmacological Validation of Zhenwu Decoction on Alleviating Isoprenaline-Induced Heart Failure Injury in Rats
por: Li, Ruiyu, et al.
Publicado: (2023)

In Vivo Antimalarial Effects of Iranian Flora Artemisia khorassanica against Plasmodium berghei and Pharmacochemistry of its Natural Components
por: Nahrevanian, H, et al.
Publicado: (2010)

Banxia Xiexin Decoction Is Effective to Prevent and Control Irinotecan-Induced Delayed Diarrhea in Recurrent Small Cell Lung Cancer
por: Lu, Hongyang, et al.
Publicado: (2018)

Integrated Serum Pharmacochemistry and Network Pharmacology Approach to Explore the Effective Components and Potential Mechanisms of Menispermi Rhizoma Against Myocardial Ischemia
por: Wei, Jinxia, et al.
Publicado: (2022)

Renal Protective Role of Xiexin Decoction with Multiple Active Ingredients Involves Inhibition of Inflammation through Downregulation of the Nuclear Factor-κB Pathway in Diabetic Rats
por: Wu, Jia-sheng, et al.
Publicado: (2013)

Integrated Serum Pharmacochemistry, Metabolomics, and Network Pharmacology to Reveal the Material Basis and Mechanism of Danggui Shaoyao San in the Treatment of Primary Dysmenorrhea
por: Xiong, Hui, et al.
Publicado: (2022)

Efficacy and Safety of Banxia XieXin Decoction, a Blended Traditional Chinese Medicine, as Monotherapy for Patients With Advanced Hepatocellular Carcinoma
por: Wang, Lijuan, et al.
Publicado: (2020)

Mechanisms of Banxia Xiexin Decoction Underlying Chronic Atrophic Gastritis via Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulations
por: Chang, Cheng, et al.
Publicado: (2022)

RNA-seq based transcriptome analysis of ethanol extract of saffron protective effect against corticosterone-induced PC12 cell injury
por: Chen, Xi, et al.
Publicado: (2022)

Pharmacological activities and effective substances of the component-based Chinese medicine of Ginkgo biloba leaves based on serum pharmacochemistry, metabonomics and network pharmacology
por: Liang, Hongbao, et al.
Publicado: (2023)

Metabolomic profiling combined with network analysis of serum pharmacochemistry to reveal the therapeutic mechanism of Ardisiae Japonicae Herba against acute lung injury
por: Han, Xiao-Xiao, et al.
Publicado: (2023)

Shengjiang San alleviated sepsis-induced lung injury through its bidirectional regulatory effect
por: Yan, Shifan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9pidp3r19t1fch277paof2edi8