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Systemic lupus erythematosus nephritis and COVID-19 disease

Of the more than 20 studies published on SLE patients with COVID-19, none of the studies focused on lupus nephritis. We report the outcomes of renal biopsy-proven systemic lupus erythematosus (SLE) nephritis patients after COVID-19 disease. Our institute has been declared as a state COVID-19 hospita...

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Autores principales: Gayathri, C., Monica, K., Lakshmi, P. Aishwarya, Mathini, S., Kumar, N. Prasanna, Ram, Kumar, V. Siva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189213/
https://www.ncbi.nlm.nih.gov/pubmed/37195372
http://dx.doi.org/10.1007/s10067-023-06634-4
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author Gayathri, C.
Monica, K.
Lakshmi, P. Aishwarya
Mathini, S.
Kumar, N. Prasanna
Ram
Kumar, V. Siva
author_facet Gayathri, C.
Monica, K.
Lakshmi, P. Aishwarya
Mathini, S.
Kumar, N. Prasanna
Ram
Kumar, V. Siva
author_sort Gayathri, C.
collection PubMed
description Of the more than 20 studies published on SLE patients with COVID-19, none of the studies focused on lupus nephritis. We report the outcomes of renal biopsy-proven systemic lupus erythematosus (SLE) nephritis patients after COVID-19 disease. Our institute has been declared as a state COVID-19 hospital in the last week of March 2020. From then till now, we have admitted and managed COVID-19 patients from several districts of Andhra Pradesh and neighbouring states. We collected the data of patients with SLE nephritis contemporaneously from admission to the outcomes on a computerised proforma. We had identified sixteen patients with SLE nephritis who were admitted with COVID-19 disease. Of them, fourteen were females and two were males. The mean age was 29.3 years. Out of sixteen patients, seven required a mechanical ventilator and dialysis and eventually succumbed. One more patient died due to disseminated tuberculosis. Our results suggested that with an approximately 50% mortality rate, the COVID-19 disease had a calamitous effect on SLE nephritis patients.
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spelling pubmed-101892132023-05-19 Systemic lupus erythematosus nephritis and COVID-19 disease Gayathri, C. Monica, K. Lakshmi, P. Aishwarya Mathini, S. Kumar, N. Prasanna Ram Kumar, V. Siva Clin Rheumatol Brief Report Of the more than 20 studies published on SLE patients with COVID-19, none of the studies focused on lupus nephritis. We report the outcomes of renal biopsy-proven systemic lupus erythematosus (SLE) nephritis patients after COVID-19 disease. Our institute has been declared as a state COVID-19 hospital in the last week of March 2020. From then till now, we have admitted and managed COVID-19 patients from several districts of Andhra Pradesh and neighbouring states. We collected the data of patients with SLE nephritis contemporaneously from admission to the outcomes on a computerised proforma. We had identified sixteen patients with SLE nephritis who were admitted with COVID-19 disease. Of them, fourteen were females and two were males. The mean age was 29.3 years. Out of sixteen patients, seven required a mechanical ventilator and dialysis and eventually succumbed. One more patient died due to disseminated tuberculosis. Our results suggested that with an approximately 50% mortality rate, the COVID-19 disease had a calamitous effect on SLE nephritis patients. Springer International Publishing 2023-05-17 /pmc/articles/PMC10189213/ /pubmed/37195372 http://dx.doi.org/10.1007/s10067-023-06634-4 Text en © The Author(s), under exclusive licence to International League of Associations for Rheumatology (ILAR) 2023 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Brief Report
Gayathri, C.
Monica, K.
Lakshmi, P. Aishwarya
Mathini, S.
Kumar, N. Prasanna
Ram
Kumar, V. Siva
Systemic lupus erythematosus nephritis and COVID-19 disease
title Systemic lupus erythematosus nephritis and COVID-19 disease
title_full Systemic lupus erythematosus nephritis and COVID-19 disease
title_fullStr Systemic lupus erythematosus nephritis and COVID-19 disease
title_full_unstemmed Systemic lupus erythematosus nephritis and COVID-19 disease
title_short Systemic lupus erythematosus nephritis and COVID-19 disease
title_sort systemic lupus erythematosus nephritis and covid-19 disease
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189213/
https://www.ncbi.nlm.nih.gov/pubmed/37195372
http://dx.doi.org/10.1007/s10067-023-06634-4
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