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Activation of NR1H3 attenuates the severity of septic myocardial injury by inhibiting NLRP3 inflammasome

Most sepsis deaths are due to the development of multiple organ failure, in which heart failure is a recognized manifestation of sepsis. To date, the role of liver X receptors α (NR1H3) in sepsis is still uncertain. Here, we hypothesized that NR1H3 mediates multiple essential sepsis‐related signalin...

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Detalles Bibliográficos
Autores principales: Deng, Chao, Liu, Qiong, Zhao, Huadong, Qian, Lu, Lei, Wangrui, Yang, Wenwen, Liang, Zhenxing, Tian, Ye, Zhang, Shaofei, Wang, Changyu, Chen, Ying, Yang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189481/
https://www.ncbi.nlm.nih.gov/pubmed/37206244
http://dx.doi.org/10.1002/btm2.10517