Quantification of the density and morphology of dendritic spines and synaptic protein distribution using Thy1-YFP transgenic mice

Synaptopathy, which encompasses morphological deficits and any abnormal protein distribution of synapses, is a critical feature of many neurological diseases. We here provide a protocol using mice stably expressing a Thy1-YFP transgene to assess synaptic features in vivo. We describe steps for recor...

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Detalles Bibliográficos
Autores principales: Lin, Yung-Jui, Huang, Tzyy-Nan, Hsueh, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189545/
https://www.ncbi.nlm.nih.gov/pubmed/37149854
http://dx.doi.org/10.1016/j.xpro.2023.102290

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