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IL‑37 suppresses macrophage ferroptosis to attenuate diabetic atherosclerosis via the NRF2 pathway

IL-37 is a newly discovered inflammatory factor. However, the protective effect and underlying mechanisms of IL-37 on atherosclerosis remain unclear. In the present study, IL-37 was used for intraperitoneal injection in diabetic ApoE(-/-) mice caused by streptozotocin. High glucose (HG)/ox-LDL was u...

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Detalles Bibliográficos
Autores principales: Xu, Jinmei, Han, Xu, Xia, Nan, Zhao, Qingsong, Cheng, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189585/
https://www.ncbi.nlm.nih.gov/pubmed/37206550
http://dx.doi.org/10.3892/etm.2023.11988

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