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Characterization of Drug-Specific CD4(+) T-Cells Reveals Possible Roles of HLA Class II in the Pathogenesis of Carbamazepine Hypersensitivity Reactions

[Image: see text] Carbamazepine (CBZ) is an aromatic anticonvulsant known to cause drug hypersensitivity reactions, which range in severity from relatively mild maculopapular exanthema to potentially fatal Stevens–Johnson syndrome and toxic epidermal necrolysis (SJS–TEN). These reactions are known t...

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Detalles Bibliográficos
Autores principales:	Jaruthamsophon, Kanoot, Thomson, Paul J., Hammond, Sean, Zhang, Eunice, Alfirevic, Ana, Sukasem, Chonlaphat, Naisbitt, Dean J., Pirmohamed, Munir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189794/ https://www.ncbi.nlm.nih.gov/pubmed/37074725 http://dx.doi.org/10.1021/acs.chemrestox.2c00414

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