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Interleukin 36 receptor-inducible matrix metalloproteinase 13 mediates intestinal fibrosis

BACKGROUND: Fibrostenotic disease is a common complication in Crohn’s disease (CD) patients hallmarked by transmural extracellular matrix (ECM) accumulation in the intestinal wall. The prevention and medical therapy of fibrostenotic CD is an unmet high clinical need. Although targeting IL36R signali...

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Detalles Bibliográficos
Autores principales:	Koop, Kristina, Enderle, Karin, Hillmann, Miriam, Ruspeckhofer, Laura, Vieth, Michael, Sturm, Gregor, Trajanoski, Zlatko, Kühl, Anja A., Atreya, Raja, Leppkes, Moritz, Baum, Patrick, Roy, Janine, Martin, Andrea, Neurath, Markus F., Neufert, Clemens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189878/ https://www.ncbi.nlm.nih.gov/pubmed/37207229 http://dx.doi.org/10.3389/fimmu.2023.1163198

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