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Synthesis of biolabile thioalkyl-protected phosphates from an easily accessible phosphotriester precursor
Robust methods for the synthesis of mixed phosphotriesters are essential to accelerate the development of novel phosphate-containing bioactive molecules. To enable efficient cellular uptake, phosphate groups are commonly masked with biolabile protecting groups, such as S-acyl-2-thioethyl (SATE) este...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189884/ https://www.ncbi.nlm.nih.gov/pubmed/37206382 http://dx.doi.org/10.1039/d3sc00693j |