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Cascade autohydrolysis of Alzheimer's Aβ peptides

Protein/peptide self-assembly into amyloid structures associates with major neurodegenerative disorders such as Alzheimer's disease (AD). Soluble assemblies (oligomers) of the Aβ peptide and their aggregates are perceived as neurotoxic species in AD. While screening for synthetic cleavage agent...

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Detalles Bibliográficos
Autores principales:	Wolfram, Martin, Tiwari, Manish K., Hassenkam, Tue, Li, Ming, Bjerrum, Morten J., Meldal, Morten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189894/ https://www.ncbi.nlm.nih.gov/pubmed/37206405 http://dx.doi.org/10.1039/d2sc06668h

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