MUS81 cleaves TOP1-derived lesions and other DNA–protein cross-links

BACKGROUND: DNA-protein cross-links (DPCs) are one of the most deleterious DNA lesions, originating from various sources, including enzymatic activity. For instance, topoisomerases, which play a fundamental role in DNA metabolic processes such as replication and transcription, can be trapped and rem...

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Detalles Bibliográficos
Autores principales: Marini, Victoria, Nikulenkov, Fedor, Samadder, Pounami, Juul, Sissel, Knudsen, Birgitta R., Krejci, Lumir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189953/
https://www.ncbi.nlm.nih.gov/pubmed/37194054
http://dx.doi.org/10.1186/s12915-023-01614-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189953/
https://www.ncbi.nlm.nih.gov/pubmed/37194054
http://dx.doi.org/10.1186/s12915-023-01614-1

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