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MUS81 cleaves TOP1-derived lesions and other DNA–protein cross-links
BACKGROUND: DNA-protein cross-links (DPCs) are one of the most deleterious DNA lesions, originating from various sources, including enzymatic activity. For instance, topoisomerases, which play a fundamental role in DNA metabolic processes such as replication and transcription, can be trapped and rem...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189953/ https://www.ncbi.nlm.nih.gov/pubmed/37194054 http://dx.doi.org/10.1186/s12915-023-01614-1 |