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CINC-2 and miR-199a-5p in EVs secreted by transplanted Thy1(+) cells activate hepatocytic progenitor cell growth in rat liver regeneration

BACKGROUND: Small hepatocyte-like progenitor cells (SHPCs) are hepatocytic progenitor cells that transiently form clusters in rat livers treated with retrorsine (Ret) that underwent 70% partial hepatectomy (PH). We previously reported that transplantation of Thy1(+) cells obtained from d-galactosami...

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Detalles Bibliográficos
Autores principales: Ichinohe, Norihisa, Tanimizu, Naoki, Ishigami, Keisuke, Yoshioka, Yusuke, Fujitani, Naoki, Ochiya, Takahiro, Takahashi, Motoko, Mitaka, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190025/
https://www.ncbi.nlm.nih.gov/pubmed/37194082
http://dx.doi.org/10.1186/s13287-023-03346-z

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