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Glucose metabolic upregulation via phosphorylation of S6 ribosomal protein affects tumor progression in distal cholangiocarcinoma

BACKGROUND: The prognosis of distal cholangiocarcinoma (dCCA) remains poor; thus, the identification of new therapeutic targets is warranted. Phosphorylated S6 ribosomal protein indicates a mammalian target of rapamycin complex 1 (mTORC1) activity, and mTORC1 plays a central role in controlling cell...

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Detalles Bibliográficos
Autores principales: Fujinaga, Atsuro, Hirashita, Teijiro, Hirashita, Yuka, Sakai, Kumiko, Kawamura, Masahiro, Masuda, Takashi, Endo, Yuichi, Ohta, Masayuki, Murakami, Kazunari, Inomata, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190040/
https://www.ncbi.nlm.nih.gov/pubmed/37193984
http://dx.doi.org/10.1186/s12876-023-02815-2