Celloscope: a probabilistic model for marker-gene-driven cell type deconvolution in spatial transcriptomics data

Spatial transcriptomics maps gene expression across tissues, posing the challenge of determining the spatial arrangement of different cell types. However, spatial transcriptomics spots contain multiple cells. Therefore, the observed signal comes from mixtures of cells of different types. Here, we pr...

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Detalles Bibliográficos
Autores principales: Geras, Agnieszka, Darvish Shafighi, Shadi, Domżał, Kacper, Filipiuk, Igor, Rączkowska, Alicja, Szymczak, Paulina, Toosi, Hosein, Kaczmarek, Leszek, Koperski, Łukasz, Lagergren, Jens, Nowis, Dominika, Szczurek, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190053/
https://www.ncbi.nlm.nih.gov/pubmed/37198601
http://dx.doi.org/10.1186/s13059-023-02951-8

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