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Activation of a hypothalamus-habenula circuit by mechanical stimulation inhibits cocaine addiction-like behaviors

BACKGROUND: Mechanoreceptor activation modulates GABA neuron firing and dopamine (DA) release in the mesolimbic DA system, an area implicated in reward and substance abuse. The lateral habenula (LHb), the lateral hypothalamus (LH), and the mesolimbic DA system are not only reciprocally connected, bu...

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Detalles Bibliográficos
Autores principales: Jang, Han Byeol, Ahn, DanBi, Chang, Suchan, Kim, Hyung Kyu, Lee, Bong Hyo, Kim, Sang Chan, Steffensen, Scott C., Bills, Kyle B., Lee, Hubert, Kim, Hee Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190066/
https://www.ncbi.nlm.nih.gov/pubmed/37194106
http://dx.doi.org/10.1186/s40659-023-00440-7