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Six-month follow-up of salivary antioxidant defense outcomes of individuals using medicated toothpaste

OBJECTIVE: The objective of this study was to study the effect of medicated toothpaste on oral health, a 6-month follow-up. METHODS: Four hundred and twenty-seven participants were screened and followed up for 6 months. The intraoral examination was performed to record caries, gingival bleeding, and...

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Autores principales: Hegde, Mithra N., Kumari, N. Suchetha, Shetty, Nireeksha, Lakshmi, V. Chaithra, Hegde, Nidarsh Divakar, Hegde, Nishmitha N., Singh, Jyoti, Sirdesai, Amit, Bandyopadhyay, Prasun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190079/
https://www.ncbi.nlm.nih.gov/pubmed/37205881
http://dx.doi.org/10.4103/jcd.jcd_542_22
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author Hegde, Mithra N.
Kumari, N. Suchetha
Shetty, Nireeksha
Lakshmi, V. Chaithra
Hegde, Nidarsh Divakar
Hegde, Nishmitha N.
Singh, Jyoti
Sirdesai, Amit
Bandyopadhyay, Prasun
author_facet Hegde, Mithra N.
Kumari, N. Suchetha
Shetty, Nireeksha
Lakshmi, V. Chaithra
Hegde, Nidarsh Divakar
Hegde, Nishmitha N.
Singh, Jyoti
Sirdesai, Amit
Bandyopadhyay, Prasun
author_sort Hegde, Mithra N.
collection PubMed
description OBJECTIVE: The objective of this study was to study the effect of medicated toothpaste on oral health, a 6-month follow-up. METHODS: Four hundred and twenty-seven participants were screened and followed up for 6 months. The intraoral examination was performed to record caries, gingival bleeding, and plaque index. Saliva collected was evaluated for pH, total antioxidant capacity (TAC), malondialdehyde (MDA), and Vitamin C level for 6 months, and data were analyzed. RESULTS: On the usage of medicated toothpaste with herbal extract for 6 months, the salivary pH levels were increased, the interquartile range for plaque, and the gingival bleeding index decreased. The percentage change in salivary TAC, MDA, and Vitamin C levels in the caries-free group of subgroup I was 174.8, 58.06, and 59.98, respectively, in subgroup II was 133.3, 52.08, and 58.51, and in subgroup III was 63.77, 45.11, and 47.77. The percentage change in salivary TAC, MDA, and Vitamin C levels in the caries-active group of subgroup I was 136.62, 57.27, and 72.83, subgroup II was 108.59, 37.50, and 61.55, and in subgroup III was 35.62, 30.82, and 54.10, respectively. CONCLUSION: The salivary pH levels increased on the usage of medicated toothpaste with herbal extract; plaque and the gingival bleeding index scores were decreased. The salivary antioxidant defense was increased in individuals using medicated toothpaste with herbal extracts which signifies an improvement in overall oral health in the 6-month follow-up.
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spelling pubmed-101900792023-05-18 Six-month follow-up of salivary antioxidant defense outcomes of individuals using medicated toothpaste Hegde, Mithra N. Kumari, N. Suchetha Shetty, Nireeksha Lakshmi, V. Chaithra Hegde, Nidarsh Divakar Hegde, Nishmitha N. Singh, Jyoti Sirdesai, Amit Bandyopadhyay, Prasun J Conserv Dent Original Article OBJECTIVE: The objective of this study was to study the effect of medicated toothpaste on oral health, a 6-month follow-up. METHODS: Four hundred and twenty-seven participants were screened and followed up for 6 months. The intraoral examination was performed to record caries, gingival bleeding, and plaque index. Saliva collected was evaluated for pH, total antioxidant capacity (TAC), malondialdehyde (MDA), and Vitamin C level for 6 months, and data were analyzed. RESULTS: On the usage of medicated toothpaste with herbal extract for 6 months, the salivary pH levels were increased, the interquartile range for plaque, and the gingival bleeding index decreased. The percentage change in salivary TAC, MDA, and Vitamin C levels in the caries-free group of subgroup I was 174.8, 58.06, and 59.98, respectively, in subgroup II was 133.3, 52.08, and 58.51, and in subgroup III was 63.77, 45.11, and 47.77. The percentage change in salivary TAC, MDA, and Vitamin C levels in the caries-active group of subgroup I was 136.62, 57.27, and 72.83, subgroup II was 108.59, 37.50, and 61.55, and in subgroup III was 35.62, 30.82, and 54.10, respectively. CONCLUSION: The salivary pH levels increased on the usage of medicated toothpaste with herbal extract; plaque and the gingival bleeding index scores were decreased. The salivary antioxidant defense was increased in individuals using medicated toothpaste with herbal extracts which signifies an improvement in overall oral health in the 6-month follow-up. Wolters Kluwer - Medknow 2023 2023-03-16 /pmc/articles/PMC10190079/ /pubmed/37205881 http://dx.doi.org/10.4103/jcd.jcd_542_22 Text en Copyright: © 2023 Journal of Conservative Dentistry https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Hegde, Mithra N.
Kumari, N. Suchetha
Shetty, Nireeksha
Lakshmi, V. Chaithra
Hegde, Nidarsh Divakar
Hegde, Nishmitha N.
Singh, Jyoti
Sirdesai, Amit
Bandyopadhyay, Prasun
Six-month follow-up of salivary antioxidant defense outcomes of individuals using medicated toothpaste
title Six-month follow-up of salivary antioxidant defense outcomes of individuals using medicated toothpaste
title_full Six-month follow-up of salivary antioxidant defense outcomes of individuals using medicated toothpaste
title_fullStr Six-month follow-up of salivary antioxidant defense outcomes of individuals using medicated toothpaste
title_full_unstemmed Six-month follow-up of salivary antioxidant defense outcomes of individuals using medicated toothpaste
title_short Six-month follow-up of salivary antioxidant defense outcomes of individuals using medicated toothpaste
title_sort six-month follow-up of salivary antioxidant defense outcomes of individuals using medicated toothpaste
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190079/
https://www.ncbi.nlm.nih.gov/pubmed/37205881
http://dx.doi.org/10.4103/jcd.jcd_542_22
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