Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis

In a recent paper in Science, Chen et al. reported the genetic engineering of S. epidermidis expressing tumor cross-reactive antigens that trigger T cell responses and exhibit anticancer effects after topical administration. Here we discuss direct local effects and indirect systemic effects of expos...

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Detalles Bibliográficos
Autores principales: Kepp, Oliver, Zitvogel, Laurence, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190176/
https://www.ncbi.nlm.nih.gov/pubmed/37205984
http://dx.doi.org/10.1080/2162402X.2023.2212547
Descripción
Sumario:In a recent paper in Science, Chen et al. reported the genetic engineering of S. epidermidis expressing tumor cross-reactive antigens that trigger T cell responses and exhibit anticancer effects after topical administration. Here we discuss direct local effects and indirect systemic effects of exposure to engineered S. epidermidis strains.

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