Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis

In a recent paper in Science, Chen et al. reported the genetic engineering of S. epidermidis expressing tumor cross-reactive antigens that trigger T cell responses and exhibit anticancer effects after topical administration. Here we discuss direct local effects and indirect systemic effects of expos...

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Detalles Bibliográficos
Autores principales: Kepp, Oliver, Zitvogel, Laurence, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190176/
https://www.ncbi.nlm.nih.gov/pubmed/37205984
http://dx.doi.org/10.1080/2162402X.2023.2212547
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author Kepp, Oliver
Zitvogel, Laurence
Kroemer, Guido
author_facet Kepp, Oliver
Zitvogel, Laurence
Kroemer, Guido
author_sort Kepp, Oliver
collection PubMed
description In a recent paper in Science, Chen et al. reported the genetic engineering of S. epidermidis expressing tumor cross-reactive antigens that trigger T cell responses and exhibit anticancer effects after topical administration. Here we discuss direct local effects and indirect systemic effects of exposure to engineered S. epidermidis strains.
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spelling pubmed-101901762023-05-18 Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis Kepp, Oliver Zitvogel, Laurence Kroemer, Guido Oncoimmunology Editorial In a recent paper in Science, Chen et al. reported the genetic engineering of S. epidermidis expressing tumor cross-reactive antigens that trigger T cell responses and exhibit anticancer effects after topical administration. Here we discuss direct local effects and indirect systemic effects of exposure to engineered S. epidermidis strains. Taylor & Francis 2023-05-15 /pmc/articles/PMC10190176/ /pubmed/37205984 http://dx.doi.org/10.1080/2162402X.2023.2212547 Text en © 2023 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.
spellingShingle Editorial
Kepp, Oliver
Zitvogel, Laurence
Kroemer, Guido
Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis
title Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis
title_full Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis
title_fullStr Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis
title_full_unstemmed Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis
title_short Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidis
title_sort prevention and treatment of cancers by tumor antigen-expressing staphylococcus epidermidis
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190176/
https://www.ncbi.nlm.nih.gov/pubmed/37205984
http://dx.doi.org/10.1080/2162402X.2023.2212547
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