Bacterial and metabolic phenotypes associated with inadequate response to ursodeoxycholic acid treatment in primary biliary cholangitis

Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease with ursodeoxycholic acid (UDCA) as first-line treatment. Poor response to UDCA is associated with a higher risk of progressing to cirrhosis, but the underlying mechanisms are unclear. UDCA modulates the composition of primary...

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Detalles Bibliográficos
Autores principales: Martinez-Gili, Laura, Pechlivanis, Alexandros, McDonald, Julie A.K., Begum, Sofina, Badrock, Jonathan, Dyson, Jessica K., Jones, Rebecca, Hirschfield, Gideon, Ryder, Stephen D., Sandford, Richard, Rushbrook, Simon, Thorburn, Douglas, Taylor-Robinson, Simon D., Crossey, Mary M.E., Marchesi, Julian R., Mells, George, Holmes, Elaine, Jones, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190197/
https://www.ncbi.nlm.nih.gov/pubmed/37191344
http://dx.doi.org/10.1080/19490976.2023.2208501

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