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AQP4 Aggravates Cognitive Impairment in Sepsis‐Associated Encephalopathy through Inhibiting Na(v)1.6‐Mediated Astrocyte Autophagy

The pathology of sepsis‐associated encephalopathy (SAE) is related to astrocyte‐inflammation associated with aquaporin‐4 (AQP4). The aim here is to investigate the effects of AQP4 associated with SAE and reveal its underlying mechanism causing cognitive impairment. The in vivo experimental results r...

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Detalles Bibliográficos
Autores principales: Zhu, Dan‐Dan, Huang, Yue‐Lin, Guo, Song‐Yu, Li, Na, Yang, Xue‐Wei, Sui, Ao‐Ran, Wu, Qiong, Zhang, Yue, Kong, Yue, Li, Qi‐Fa, Zhang, Ting, Zheng, Wen‐Fei, Li, Ai‐Ping, Yu, Jian, Ma, Tong‐Hui, Li, Shao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190498/
https://www.ncbi.nlm.nih.gov/pubmed/36922751
http://dx.doi.org/10.1002/advs.202205862