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AQP4 Aggravates Cognitive Impairment in Sepsis‐Associated Encephalopathy through Inhibiting Na(v)1.6‐Mediated Astrocyte Autophagy
The pathology of sepsis‐associated encephalopathy (SAE) is related to astrocyte‐inflammation associated with aquaporin‐4 (AQP4). The aim here is to investigate the effects of AQP4 associated with SAE and reveal its underlying mechanism causing cognitive impairment. The in vivo experimental results r...
Autores principales: | Zhu, Dan‐Dan, Huang, Yue‐Lin, Guo, Song‐Yu, Li, Na, Yang, Xue‐Wei, Sui, Ao‐Ran, Wu, Qiong, Zhang, Yue, Kong, Yue, Li, Qi‐Fa, Zhang, Ting, Zheng, Wen‐Fei, Li, Ai‐Ping, Yu, Jian, Ma, Tong‐Hui, Li, Shao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190498/ https://www.ncbi.nlm.nih.gov/pubmed/36922751 http://dx.doi.org/10.1002/advs.202205862 |
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