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The inhibition of ORMDL3 prevents Alzheimer's disease through ferroptosis by PERK/ATF4/HSPA5 pathway

Alzheimer's disease (AD) is a neurodegenerative disease with high incidence and widespread attention. There is currently no clear clarification of the pathogenesis. However, ORMDL3 causes ferroptosis in AD, and the potential mechanisms remain unclear. So, this study explore the function of ORMD...

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Detalles Bibliográficos
Autores principales: Shao, Yankun, Xu, Yilin, Di, Huang, Shi, Xinxiu, Wang, Yingying, Liu, Hongyu, Song, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190607/
https://www.ncbi.nlm.nih.gov/pubmed/36680386
http://dx.doi.org/10.1049/nbt2.12113

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