Rapidly Inhibiting the Inflammatory Cytokine Storms and Restoring Cellular Homeostasis to Alleviate Sepsis by Blocking Pyroptosis and Mitochondrial Apoptosis Pathways

Pyroptosis, systemic inflammation, and mitochondrial apoptosis are the three primary contributors to sepsis's multiple organ failure, the ultimate cause of high clinical mortality. Currently, the drugs under development only target a single pathogenesis, which is obviously insufficient. In this...

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Detalles Bibliográficos
Autores principales: Yan, Jiahui, Zhang, Jingwen, Wang, Yanan, Liu, Hong, Sun, Xueping, Li, Aixin, Cui, Pengfei, Yu, Liangmin, Yan, Xuefeng, He, Zhiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190643/
https://www.ncbi.nlm.nih.gov/pubmed/36932048
http://dx.doi.org/10.1002/advs.202207448

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