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Comparison between metabolic-associated fatty liver disease and nonalcoholic fatty liver disease: From nomenclature to clinical outcomes

As a result of the obesity epidemic, Nonalcoholic fatty liver disease (NAFLD) and its complications have increased among millions of people. Consequently, a group of experts recommended changing the term NAFLD to an inclusive terminology more reflective of the underlying pathogenesis; metabolic-asso...

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Detalles Bibliográficos
Autores principales: Alomari, Mohammad, Rashid, Mamoon Ur, Chadalavada, Pravallika, Ragheb, Jonathan, Zafar, Hammad, Suarez, Zoilo Karim, Khazaaleh, Shrouq, Gonzalez, Adalberto Jose, Castro, Fernando J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190689/
https://www.ncbi.nlm.nih.gov/pubmed/37206648
http://dx.doi.org/10.4254/wjh.v15.i4.477
Descripción
Sumario:As a result of the obesity epidemic, Nonalcoholic fatty liver disease (NAFLD) and its complications have increased among millions of people. Consequently, a group of experts recommended changing the term NAFLD to an inclusive terminology more reflective of the underlying pathogenesis; metabolic-associated fatty liver disease (MAFLD). This new term of MAFLD has its own disease epidemiology and clinical outcomes prompting efforts in studying its differences from NAFLD. This article discusses the rationale behind the nomenclature change, the main differences, and its clinical implications.