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Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway

BACKGROUND: The incidence rate of acute pancreatitis (AP), which is a pathophysiological process with complex etiology, is increasing globally. miR-125b-5p, a bidirectional regulatory miRNA, is speculated to exhibit anti-tumor activity. However, exosome-derived miR-125b-5p in AP has not been reporte...

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Detalles Bibliográficos
Autores principales: Zheng, Zhi, Cao, Feng, Ding, Yi-Xuan, Lu, Jiong-Di, Fu, Yuan-Qiao, Liu, Lin, Guo, Yu-Lin, Liu, Shuang, Sun, Hai-Chen, Cui, Ye-Qing, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190724/
https://www.ncbi.nlm.nih.gov/pubmed/37206078
http://dx.doi.org/10.4240/wjgs.v15.i4.600