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Role of bioaerosol in virus transmission and material‐based countermeasures

Respiratory pathogens transmit primarily through particles such as droplets and aerosols. Although often overlooked, the resuspension of settled droplets is also a key facilitator of disease transmission. In this review, we discuss the three main mechanisms of aerosol generation: direct generation s...

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Autores principales: Joseph, John, Baby, Helna Mary, Zhao, Spencer, Li, Xiang‐Ling, Cheung, Krisco‐Cheuk, Swain, Kabir, Agus, Eli, Ranganathan, Sruthi, Gao, Jingjing, Luo, James N, Joshi, Nitin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190935/
https://www.ncbi.nlm.nih.gov/pubmed/37324804
http://dx.doi.org/10.1002/EXP.20210038
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author Joseph, John
Baby, Helna Mary
Zhao, Spencer
Li, Xiang‐Ling
Cheung, Krisco‐Cheuk
Swain, Kabir
Agus, Eli
Ranganathan, Sruthi
Gao, Jingjing
Luo, James N
Joshi, Nitin
author_facet Joseph, John
Baby, Helna Mary
Zhao, Spencer
Li, Xiang‐Ling
Cheung, Krisco‐Cheuk
Swain, Kabir
Agus, Eli
Ranganathan, Sruthi
Gao, Jingjing
Luo, James N
Joshi, Nitin
author_sort Joseph, John
collection PubMed
description Respiratory pathogens transmit primarily through particles such as droplets and aerosols. Although often overlooked, the resuspension of settled droplets is also a key facilitator of disease transmission. In this review, we discuss the three main mechanisms of aerosol generation: direct generation such as coughing and sneezing, indirect generation such as medical procedures, and resuspension of settled droplets and aerosols. The size of particles and environmental factors influence their airborne lifetime and ability to cause infection. Specifically, humidity and temperature are key factors controlling the evaporation of suspended droplets, consequently affecting the duration in which particles remain airborne. We also suggest material‐based approaches for effective prevention of disease transmission. These approaches include electrostatically charged virucidal agents and surface coatings, which have been shown to be highly effective in deactivating and reducing resuspension of pathogen‐laden aerosols.
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spelling pubmed-101909352023-06-14 Role of bioaerosol in virus transmission and material‐based countermeasures Joseph, John Baby, Helna Mary Zhao, Spencer Li, Xiang‐Ling Cheung, Krisco‐Cheuk Swain, Kabir Agus, Eli Ranganathan, Sruthi Gao, Jingjing Luo, James N Joshi, Nitin Exploration (Beijing) Reviews Respiratory pathogens transmit primarily through particles such as droplets and aerosols. Although often overlooked, the resuspension of settled droplets is also a key facilitator of disease transmission. In this review, we discuss the three main mechanisms of aerosol generation: direct generation such as coughing and sneezing, indirect generation such as medical procedures, and resuspension of settled droplets and aerosols. The size of particles and environmental factors influence their airborne lifetime and ability to cause infection. Specifically, humidity and temperature are key factors controlling the evaporation of suspended droplets, consequently affecting the duration in which particles remain airborne. We also suggest material‐based approaches for effective prevention of disease transmission. These approaches include electrostatically charged virucidal agents and surface coatings, which have been shown to be highly effective in deactivating and reducing resuspension of pathogen‐laden aerosols. John Wiley and Sons Inc. 2022-05-23 /pmc/articles/PMC10190935/ /pubmed/37324804 http://dx.doi.org/10.1002/EXP.20210038 Text en © 2022 The Authors. Exploration published by Henan University and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Joseph, John
Baby, Helna Mary
Zhao, Spencer
Li, Xiang‐Ling
Cheung, Krisco‐Cheuk
Swain, Kabir
Agus, Eli
Ranganathan, Sruthi
Gao, Jingjing
Luo, James N
Joshi, Nitin
Role of bioaerosol in virus transmission and material‐based countermeasures
title Role of bioaerosol in virus transmission and material‐based countermeasures
title_full Role of bioaerosol in virus transmission and material‐based countermeasures
title_fullStr Role of bioaerosol in virus transmission and material‐based countermeasures
title_full_unstemmed Role of bioaerosol in virus transmission and material‐based countermeasures
title_short Role of bioaerosol in virus transmission and material‐based countermeasures
title_sort role of bioaerosol in virus transmission and material‐based countermeasures
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190935/
https://www.ncbi.nlm.nih.gov/pubmed/37324804
http://dx.doi.org/10.1002/EXP.20210038
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