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Engineered cancer cell membranes: An emerging agent for efficient cancer theranostics

For efficient cancer theranostics, surface modification of nanomaterials plays an important role in improving targeting ability and reducing the non‐specific interactions with normal tissues. Recently, the biomimetic technology represented by coating of cancer cell membranes (CCMs) has been regarded...

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Detalles Bibliográficos
Autores principales: Guo, Yunqi, Wang, Zhiqiang, Shi, Xiangyang, Shen, Mingwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190949/
https://www.ncbi.nlm.nih.gov/pubmed/37324583
http://dx.doi.org/10.1002/EXP.20210171
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author Guo, Yunqi
Wang, Zhiqiang
Shi, Xiangyang
Shen, Mingwu
author_facet Guo, Yunqi
Wang, Zhiqiang
Shi, Xiangyang
Shen, Mingwu
author_sort Guo, Yunqi
collection PubMed
description For efficient cancer theranostics, surface modification of nanomaterials plays an important role in improving targeting ability and reducing the non‐specific interactions with normal tissues. Recently, the biomimetic technology represented by coating of cancer cell membranes (CCMs) has been regarded as a promising method to strengthen the biocompatibility and targeting specificity of nanomaterials. Furthermore, the engineered CCMs (ECCMs) integrated with the natural biological properties of CCMs and specific functions from other cells or proteins have offered more possibilities in the field of cancer theranostics. Herein, the recent progresses in the design and preparation of ECCMs are summarized, and the applications of ECCMs in targeting delivery, activation of immunity, and detection of circulating tumor cells are reviewed. Finally, the current challenges and future perspectives with regard to the development of ECCMs are briefly discussed.
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spelling pubmed-101909492023-06-14 Engineered cancer cell membranes: An emerging agent for efficient cancer theranostics Guo, Yunqi Wang, Zhiqiang Shi, Xiangyang Shen, Mingwu Exploration (Beijing) Review Articles For efficient cancer theranostics, surface modification of nanomaterials plays an important role in improving targeting ability and reducing the non‐specific interactions with normal tissues. Recently, the biomimetic technology represented by coating of cancer cell membranes (CCMs) has been regarded as a promising method to strengthen the biocompatibility and targeting specificity of nanomaterials. Furthermore, the engineered CCMs (ECCMs) integrated with the natural biological properties of CCMs and specific functions from other cells or proteins have offered more possibilities in the field of cancer theranostics. Herein, the recent progresses in the design and preparation of ECCMs are summarized, and the applications of ECCMs in targeting delivery, activation of immunity, and detection of circulating tumor cells are reviewed. Finally, the current challenges and future perspectives with regard to the development of ECCMs are briefly discussed. John Wiley and Sons Inc. 2022-01-25 /pmc/articles/PMC10190949/ /pubmed/37324583 http://dx.doi.org/10.1002/EXP.20210171 Text en © 2022 The Authors. Exploration published by Henan University and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Articles
Guo, Yunqi
Wang, Zhiqiang
Shi, Xiangyang
Shen, Mingwu
Engineered cancer cell membranes: An emerging agent for efficient cancer theranostics
title Engineered cancer cell membranes: An emerging agent for efficient cancer theranostics
title_full Engineered cancer cell membranes: An emerging agent for efficient cancer theranostics
title_fullStr Engineered cancer cell membranes: An emerging agent for efficient cancer theranostics
title_full_unstemmed Engineered cancer cell membranes: An emerging agent for efficient cancer theranostics
title_short Engineered cancer cell membranes: An emerging agent for efficient cancer theranostics
title_sort engineered cancer cell membranes: an emerging agent for efficient cancer theranostics
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10190949/
https://www.ncbi.nlm.nih.gov/pubmed/37324583
http://dx.doi.org/10.1002/EXP.20210171
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