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PEGylated Tween 80-functionalized chitosan-lipidic nano-vesicular hybrids for heightening nose-to-brain delivery and bioavailability of metoclopramide

A PEGylated Tween 80–functionalized chitosan–lipidic (PEG-T-Chito-Lip) nano-vesicular hybrid was developed for intranasal administration as an alternative delivery route to help improve the poor oral bioavailability of BCS class-III model/antiemetic (metoclopramide hydrochloride; MTC). The influence...

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Detalles Bibliográficos
Autores principales:	Al-Zuhairy, Saeed A. S., Teaima, Mahmoud H., Shoman, Nabil A., Elasaly, Mohamed, El-Nabarawi, Mohamed A., El-Sawy, Hossam S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191064/ https://www.ncbi.nlm.nih.gov/pubmed/36916128 http://dx.doi.org/10.1080/10717544.2023.2189112

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