Ovariectomy Via 12/15-lipoxygenase Augments Angiotensin II-Induced Hypertension and Its Pathogenesis in Female Mice

Ang II (angiotensin II) releases arachidonic acid from tissue phospholipids that is metabolized by 12/15-lipoxygenase (ALOX15), generating 12(S)- and 15(S)-hydroxyeicosatetraenoic acid (HETE), which have been implicated in cardiovascular and renal diseases. In this study, we tested the hypothesis th...

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Detalles Bibliográficos
Autores principales: Dutta, Shubha R., Singh, Purnima, Malik, Kafait U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191208/
https://www.ncbi.nlm.nih.gov/pubmed/37021560
http://dx.doi.org/10.1161/HYPERTENSIONAHA.122.20836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191208/
https://www.ncbi.nlm.nih.gov/pubmed/37021560
http://dx.doi.org/10.1161/HYPERTENSIONAHA.122.20836

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