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Revisiting Aire and tissue-restricted antigens at single-cell resolution

The thymus is a highly specialized organ that plays an indispensable role in the establishment of self-tolerance, a process characterized by the “education” of developing T-cells. To provide competent T-cells tolerant to self-antigens, medullary thymic epithelial cells (mTECs) orchestrate negative s...

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Detalles Bibliográficos
Autores principales:	Matsumoto, Minoru, Yoshida, Hideyuki, Tsuneyama, Koichi, Oya, Takeshi, Matsumoto, Mitsuru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191227/ https://www.ncbi.nlm.nih.gov/pubmed/37207224 http://dx.doi.org/10.3389/fimmu.2023.1176450

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