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Leptin deficiency in CD8(+) T cells ameliorates non-segmental vitiligo by reducing interferon-γ and Granzyme B

BACKGROUND: Vitiligo is an autoimmune skin disease mainly mediated by CD8(+) T cells, which affects about 0.1%-2% population of the world. Leptin plays a critical role in regulating the activation of CD8(+) T cells. However, the effect of Leptin on vitiligo remains unclear. OBJECTIVES: To explore th...

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Detalles Bibliográficos
Autores principales:	Wu, Meiyu, Wang, Lu, Wu, Haijing, Yang, Ming, He, Zhenghao, Chen, Yiran, Zhang, Huiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191228/ https://www.ncbi.nlm.nih.gov/pubmed/37207234 http://dx.doi.org/10.3389/fimmu.2023.1158883

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