Cross-reactive EBNA1 immunity targets alpha-crystallin B and is associated with multiple sclerosis

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system, for which Epstein-Barr virus (EBV) infection is a likely prerequisite. Due to the homology between Epstein-Barr nuclear antigen 1 (EBNA1) and alpha-crystallin B (CRYAB), we examined antibody reactivity to EBNA1 and CRY...

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Detalles Bibliográficos
Autores principales: Thomas, Olivia G., Bronge, Mattias, Tengvall, Katarina, Akpinar, Birce, Nilsson, Ola B., Holmgren, Erik, Hessa, Tara, Gafvelin, Guro, Khademi, Mohsen, Alfredsson, Lars, Martin, Roland, Guerreiro-Cacais, André Ortlieb, Grönlund, Hans, Olsson, Tomas, Kockum, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191428/
https://www.ncbi.nlm.nih.gov/pubmed/37196088
http://dx.doi.org/10.1126/sciadv.adg3032

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