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Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin

The infant was born at a gestational age of 28 + 2 weeks as second twin to a 26-year-old woman, G1/P0, due to eclampsia. The patient developed well and was on full oral feeds when he started to develop nonbilious vomiting at 5 weeks. He was diagnosed with pyloric hypertrophy and underwent pylorotomy...

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Autores principales: Dries, Verena, Müller, Dirk, Schnekenburger, Franz G., Berger, Irina, Rottscholl, Robert, Jenke, Andreas C.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191466/
https://www.ncbi.nlm.nih.gov/pubmed/37206597
http://dx.doi.org/10.1097/PG9.0000000000000025
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author Dries, Verena
Müller, Dirk
Schnekenburger, Franz G.
Berger, Irina
Rottscholl, Robert
Jenke, Andreas C.W.
author_facet Dries, Verena
Müller, Dirk
Schnekenburger, Franz G.
Berger, Irina
Rottscholl, Robert
Jenke, Andreas C.W.
author_sort Dries, Verena
collection PubMed
description The infant was born at a gestational age of 28 + 2 weeks as second twin to a 26-year-old woman, G1/P0, due to eclampsia. The patient developed well and was on full oral feeds when he started to develop nonbilious vomiting at 5 weeks. He was diagnosed with pyloric hypertrophy and underwent pylorotomy, but the condition did not improve and the patient was referred to our hospital. Here, esophagogastroduodenoscopy showed severely inflamed esophageal and gastric mucosa which was found to be due to cytomegaly virus (CMV) infection and a nonpassable pylorus. The patient underwent pyloroplasty revealing a fibrous pyloric ring. Histology showed giant cells suggestive of CMV infection which was confirmed by polymerase chain reaction. He was started on valganciclovir and discharged 4 weeks later on full enteral feeds. To our knowledge, this is the first case of gastric outlet obstruction due to CMV infection in a premature infant.
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spelling pubmed-101914662023-05-18 Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin Dries, Verena Müller, Dirk Schnekenburger, Franz G. Berger, Irina Rottscholl, Robert Jenke, Andreas C.W. JPGN Rep Case Report The infant was born at a gestational age of 28 + 2 weeks as second twin to a 26-year-old woman, G1/P0, due to eclampsia. The patient developed well and was on full oral feeds when he started to develop nonbilious vomiting at 5 weeks. He was diagnosed with pyloric hypertrophy and underwent pylorotomy, but the condition did not improve and the patient was referred to our hospital. Here, esophagogastroduodenoscopy showed severely inflamed esophageal and gastric mucosa which was found to be due to cytomegaly virus (CMV) infection and a nonpassable pylorus. The patient underwent pyloroplasty revealing a fibrous pyloric ring. Histology showed giant cells suggestive of CMV infection which was confirmed by polymerase chain reaction. He was started on valganciclovir and discharged 4 weeks later on full enteral feeds. To our knowledge, this is the first case of gastric outlet obstruction due to CMV infection in a premature infant. Lippincott Williams & Wilkins, Inc. 2020-11-11 /pmc/articles/PMC10191466/ /pubmed/37206597 http://dx.doi.org/10.1097/PG9.0000000000000025 Text en Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dries, Verena
Müller, Dirk
Schnekenburger, Franz G.
Berger, Irina
Rottscholl, Robert
Jenke, Andreas C.W.
Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin
title Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin
title_full Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin
title_fullStr Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin
title_full_unstemmed Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin
title_short Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin
title_sort late-onset cytomegalovirus infection associated with gastric outlet obstruction in a preterm twin
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191466/
https://www.ncbi.nlm.nih.gov/pubmed/37206597
http://dx.doi.org/10.1097/PG9.0000000000000025
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