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Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin
The infant was born at a gestational age of 28 + 2 weeks as second twin to a 26-year-old woman, G1/P0, due to eclampsia. The patient developed well and was on full oral feeds when he started to develop nonbilious vomiting at 5 weeks. He was diagnosed with pyloric hypertrophy and underwent pylorotomy...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191466/ https://www.ncbi.nlm.nih.gov/pubmed/37206597 http://dx.doi.org/10.1097/PG9.0000000000000025 |
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author | Dries, Verena Müller, Dirk Schnekenburger, Franz G. Berger, Irina Rottscholl, Robert Jenke, Andreas C.W. |
author_facet | Dries, Verena Müller, Dirk Schnekenburger, Franz G. Berger, Irina Rottscholl, Robert Jenke, Andreas C.W. |
author_sort | Dries, Verena |
collection | PubMed |
description | The infant was born at a gestational age of 28 + 2 weeks as second twin to a 26-year-old woman, G1/P0, due to eclampsia. The patient developed well and was on full oral feeds when he started to develop nonbilious vomiting at 5 weeks. He was diagnosed with pyloric hypertrophy and underwent pylorotomy, but the condition did not improve and the patient was referred to our hospital. Here, esophagogastroduodenoscopy showed severely inflamed esophageal and gastric mucosa which was found to be due to cytomegaly virus (CMV) infection and a nonpassable pylorus. The patient underwent pyloroplasty revealing a fibrous pyloric ring. Histology showed giant cells suggestive of CMV infection which was confirmed by polymerase chain reaction. He was started on valganciclovir and discharged 4 weeks later on full enteral feeds. To our knowledge, this is the first case of gastric outlet obstruction due to CMV infection in a premature infant. |
format | Online Article Text |
id | pubmed-10191466 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Lippincott Williams & Wilkins, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-101914662023-05-18 Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin Dries, Verena Müller, Dirk Schnekenburger, Franz G. Berger, Irina Rottscholl, Robert Jenke, Andreas C.W. JPGN Rep Case Report The infant was born at a gestational age of 28 + 2 weeks as second twin to a 26-year-old woman, G1/P0, due to eclampsia. The patient developed well and was on full oral feeds when he started to develop nonbilious vomiting at 5 weeks. He was diagnosed with pyloric hypertrophy and underwent pylorotomy, but the condition did not improve and the patient was referred to our hospital. Here, esophagogastroduodenoscopy showed severely inflamed esophageal and gastric mucosa which was found to be due to cytomegaly virus (CMV) infection and a nonpassable pylorus. The patient underwent pyloroplasty revealing a fibrous pyloric ring. Histology showed giant cells suggestive of CMV infection which was confirmed by polymerase chain reaction. He was started on valganciclovir and discharged 4 weeks later on full enteral feeds. To our knowledge, this is the first case of gastric outlet obstruction due to CMV infection in a premature infant. Lippincott Williams & Wilkins, Inc. 2020-11-11 /pmc/articles/PMC10191466/ /pubmed/37206597 http://dx.doi.org/10.1097/PG9.0000000000000025 Text en Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Dries, Verena Müller, Dirk Schnekenburger, Franz G. Berger, Irina Rottscholl, Robert Jenke, Andreas C.W. Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin |
title | Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin |
title_full | Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin |
title_fullStr | Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin |
title_full_unstemmed | Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin |
title_short | Late-onset Cytomegalovirus Infection Associated With Gastric Outlet Obstruction in a Preterm Twin |
title_sort | late-onset cytomegalovirus infection associated with gastric outlet obstruction in a preterm twin |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191466/ https://www.ncbi.nlm.nih.gov/pubmed/37206597 http://dx.doi.org/10.1097/PG9.0000000000000025 |
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