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Upper Gastrointestinal Bleeding as the First Presentation of Eosinophilic Gastrointestinal Disease
Gastrointestinal bleeding is a rare but potentially life-threatening manifestation of eosinophilic gastrointestinal disorders (EGIDs). Here, we describe a case series comprising 5 pediatric patients between 7 and 12 years of age, who presented to the emergency department with hematemesis and were su...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191568/ https://www.ncbi.nlm.nih.gov/pubmed/37206599 http://dx.doi.org/10.1097/PG9.0000000000000017 |
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author | Ozdogan, Elif Caglayan, Latife Doganay Mizikoglu, Ozlem Arikan, Cigdem |
author_facet | Ozdogan, Elif Caglayan, Latife Doganay Mizikoglu, Ozlem Arikan, Cigdem |
author_sort | Ozdogan, Elif |
collection | PubMed |
description | Gastrointestinal bleeding is a rare but potentially life-threatening manifestation of eosinophilic gastrointestinal disorders (EGIDs). Here, we describe a case series comprising 5 pediatric patients between 7 and 12 years of age, who presented to the emergency department with hematemesis and were subsequently diagnosed with EGID. Accompanying allergic history, peripheral eosinophilia, and total IgE elevation were common. Despite a more severe presentation, response to medical and dietary therapy was favorable. A comprehensive review of the literature revealed 26 other cases with similar findings that reinforced the importance of prompt recognition and early dietary and immunomodulating therapy in the control of this disease. |
format | Online Article Text |
id | pubmed-10191568 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Lippincott Williams & Wilkins, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-101915682023-05-18 Upper Gastrointestinal Bleeding as the First Presentation of Eosinophilic Gastrointestinal Disease Ozdogan, Elif Caglayan, Latife Doganay Mizikoglu, Ozlem Arikan, Cigdem JPGN Rep Brief Report Gastrointestinal bleeding is a rare but potentially life-threatening manifestation of eosinophilic gastrointestinal disorders (EGIDs). Here, we describe a case series comprising 5 pediatric patients between 7 and 12 years of age, who presented to the emergency department with hematemesis and were subsequently diagnosed with EGID. Accompanying allergic history, peripheral eosinophilia, and total IgE elevation were common. Despite a more severe presentation, response to medical and dietary therapy was favorable. A comprehensive review of the literature revealed 26 other cases with similar findings that reinforced the importance of prompt recognition and early dietary and immunomodulating therapy in the control of this disease. Lippincott Williams & Wilkins, Inc. 2020-11-11 /pmc/articles/PMC10191568/ /pubmed/37206599 http://dx.doi.org/10.1097/PG9.0000000000000017 Text en Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Brief Report Ozdogan, Elif Caglayan, Latife Doganay Mizikoglu, Ozlem Arikan, Cigdem Upper Gastrointestinal Bleeding as the First Presentation of Eosinophilic Gastrointestinal Disease |
title | Upper Gastrointestinal Bleeding as the First Presentation of Eosinophilic Gastrointestinal Disease |
title_full | Upper Gastrointestinal Bleeding as the First Presentation of Eosinophilic Gastrointestinal Disease |
title_fullStr | Upper Gastrointestinal Bleeding as the First Presentation of Eosinophilic Gastrointestinal Disease |
title_full_unstemmed | Upper Gastrointestinal Bleeding as the First Presentation of Eosinophilic Gastrointestinal Disease |
title_short | Upper Gastrointestinal Bleeding as the First Presentation of Eosinophilic Gastrointestinal Disease |
title_sort | upper gastrointestinal bleeding as the first presentation of eosinophilic gastrointestinal disease |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191568/ https://www.ncbi.nlm.nih.gov/pubmed/37206599 http://dx.doi.org/10.1097/PG9.0000000000000017 |
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