Cargando…
Acute Liver Failure in a Healthy Young Female With COVID-19
Several well-described manifestations of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported. Among them, a transient elevation of liver enzymes is the typical presentation of coronavirus disease 2019 (COVID-19) liver-related injury. The mechanism of liver...
| Autores principales: | , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Lippincott Williams & Wilkins, Inc.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191572/ https://www.ncbi.nlm.nih.gov/pubmed/37205955 http://dx.doi.org/10.1097/PG9.0000000000000108 |
| _version_ | 1785043490768420864 |
|---|---|
| author | Orandi, Babak John Li, Geling Dhall, Deepti Bajpai, Prachi Manne, Upender Arora, Nitin Lu, Ailing Coronado, Ana Carolina Kassel, Rachel Pinninti, Swetha Lewis, Cora Elizabeth Chapleau, Christopher Locke, Jayme Elizabeth Gutierrez Sanchez, Luz Helena |
| author_facet | Orandi, Babak John Li, Geling Dhall, Deepti Bajpai, Prachi Manne, Upender Arora, Nitin Lu, Ailing Coronado, Ana Carolina Kassel, Rachel Pinninti, Swetha Lewis, Cora Elizabeth Chapleau, Christopher Locke, Jayme Elizabeth Gutierrez Sanchez, Luz Helena |
| author_sort | Orandi, Babak John |
| collection | PubMed |
| description | Several well-described manifestations of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported. Among them, a transient elevation of liver enzymes is the typical presentation of coronavirus disease 2019 (COVID-19) liver-related injury. The mechanism of liver involvement is likely a combination of viral injury and immune-mediated inflammation. In contrast, acute liver failure in the setting of COVID-19 has rarely been reported. Herein, we report a case of pediatric acute liver failure in a previously healthy female adolescent infected with SARS-CoV-2 with biopsy evidence of replicating virus in hepatocytes, which has not been previously reported. |
| format | Online Article Text |
| id | pubmed-10191572 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Lippincott Williams & Wilkins, Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-101915722023-05-18 Acute Liver Failure in a Healthy Young Female With COVID-19 Orandi, Babak John Li, Geling Dhall, Deepti Bajpai, Prachi Manne, Upender Arora, Nitin Lu, Ailing Coronado, Ana Carolina Kassel, Rachel Pinninti, Swetha Lewis, Cora Elizabeth Chapleau, Christopher Locke, Jayme Elizabeth Gutierrez Sanchez, Luz Helena JPGN Rep Case Report Several well-described manifestations of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported. Among them, a transient elevation of liver enzymes is the typical presentation of coronavirus disease 2019 (COVID-19) liver-related injury. The mechanism of liver involvement is likely a combination of viral injury and immune-mediated inflammation. In contrast, acute liver failure in the setting of COVID-19 has rarely been reported. Herein, we report a case of pediatric acute liver failure in a previously healthy female adolescent infected with SARS-CoV-2 with biopsy evidence of replicating virus in hepatocytes, which has not been previously reported. Lippincott Williams & Wilkins, Inc. 2021-07-22 /pmc/articles/PMC10191572/ /pubmed/37205955 http://dx.doi.org/10.1097/PG9.0000000000000108 Text en Copyright © 2021 The Author(s). Published by Wolters Kluwer on behalf of European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Case Report Orandi, Babak John Li, Geling Dhall, Deepti Bajpai, Prachi Manne, Upender Arora, Nitin Lu, Ailing Coronado, Ana Carolina Kassel, Rachel Pinninti, Swetha Lewis, Cora Elizabeth Chapleau, Christopher Locke, Jayme Elizabeth Gutierrez Sanchez, Luz Helena Acute Liver Failure in a Healthy Young Female With COVID-19 |
| title | Acute Liver Failure in a Healthy Young Female With COVID-19 |
| title_full | Acute Liver Failure in a Healthy Young Female With COVID-19 |
| title_fullStr | Acute Liver Failure in a Healthy Young Female With COVID-19 |
| title_full_unstemmed | Acute Liver Failure in a Healthy Young Female With COVID-19 |
| title_short | Acute Liver Failure in a Healthy Young Female With COVID-19 |
| title_sort | acute liver failure in a healthy young female with covid-19 |
| topic | Case Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191572/ https://www.ncbi.nlm.nih.gov/pubmed/37205955 http://dx.doi.org/10.1097/PG9.0000000000000108 |
| work_keys_str_mv | AT orandibabakjohn acuteliverfailureinahealthyyoungfemalewithcovid19 AT ligeling acuteliverfailureinahealthyyoungfemalewithcovid19 AT dhalldeepti acuteliverfailureinahealthyyoungfemalewithcovid19 AT bajpaiprachi acuteliverfailureinahealthyyoungfemalewithcovid19 AT manneupender acuteliverfailureinahealthyyoungfemalewithcovid19 AT aroranitin acuteliverfailureinahealthyyoungfemalewithcovid19 AT luailing acuteliverfailureinahealthyyoungfemalewithcovid19 AT coronadoanacarolina acuteliverfailureinahealthyyoungfemalewithcovid19 AT kasselrachel acuteliverfailureinahealthyyoungfemalewithcovid19 AT pinnintiswetha acuteliverfailureinahealthyyoungfemalewithcovid19 AT lewiscoraelizabeth acuteliverfailureinahealthyyoungfemalewithcovid19 AT chapleauchristopher acuteliverfailureinahealthyyoungfemalewithcovid19 AT lockejaymeelizabeth acuteliverfailureinahealthyyoungfemalewithcovid19 AT gutierrezsanchezluzhelena acuteliverfailureinahealthyyoungfemalewithcovid19 |