Neuronal identity defines α-synuclein and tau toxicity

Pathogenic α-synuclein and tau are critical drivers of neurodegeneration, and their mutations cause neuronal loss in patients. Whether the underlying preferential neuronal vulnerability is a cell-type-intrinsic property or a consequence of increased expression levels remains elusive. Here, we explor...

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Detalles Bibliográficos
Autores principales: Praschberger, Roman, Kuenen, Sabine, Schoovaerts, Nils, Kaempf, Natalie, Singh, Jeevanjot, Janssens, Jasper, Swerts, Jef, Nachman, Eliana, Calatayud, Carles, Aerts, Stein, Poovathingal, Suresh, Verstreken, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191620/
https://www.ncbi.nlm.nih.gov/pubmed/36948206
http://dx.doi.org/10.1016/j.neuron.2023.02.033

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