Down-regulated GAS6 impairs synovial macrophage efferocytosis and promotes obesity-associated osteoarthritis

Obesity has always been considered a significant risk factor in osteoarthritis (OA) progression, but the underlying mechanism of obesity-related inflammation in OA synovitis remains unclear. The present study found that synovial macrophages infiltrated and polarized in the obesity microenvironment a...

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Detalles Bibliográficos
Autores principales: Yao, Zihao, Qi, Weizhong, Zhang, Hongbo, Zhang, Zhicheng, Liu, Liangliang, Shao, Yan, Zeng, Hua, Yin, Jianbin, Pan, Haoyan, Guo, Xiongtian, Liu, Anling, Cai, Daozhang, Bai, Xiaochun, Zhang, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191622/
https://www.ncbi.nlm.nih.gov/pubmed/37144868
http://dx.doi.org/10.7554/eLife.83069

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