Structural inventory of cotranslational protein folding by the eukaryotic RAC complex

The challenge of nascent chain folding at the ribosome is met by the conserved ribosome-associated complex (RAC), which forms a chaperone triad with the Hsp70 protein Ssb in fungi, and consists of the non-canonical Hsp70 Ssz1 and the J domain protein Zuotin (Zuo1). Here we determine cryo-EM structur...

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Detalles Bibliográficos
Autores principales: Kišonaitė, Miglė, Wild, Klemens, Lapouge, Karine, Gesé, Genís Valentín, Kellner, Nikola, Hurt, Ed, Sinning, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191838/
https://www.ncbi.nlm.nih.gov/pubmed/37081320
http://dx.doi.org/10.1038/s41594-023-00973-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191838/
https://www.ncbi.nlm.nih.gov/pubmed/37081320
http://dx.doi.org/10.1038/s41594-023-00973-1

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