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Structural inventory of cotranslational protein folding by the eukaryotic RAC complex
The challenge of nascent chain folding at the ribosome is met by the conserved ribosome-associated complex (RAC), which forms a chaperone triad with the Hsp70 protein Ssb in fungi, and consists of the non-canonical Hsp70 Ssz1 and the J domain protein Zuotin (Zuo1). Here we determine cryo-EM structur...
Autores principales: | Kišonaitė, Miglė, Wild, Klemens, Lapouge, Karine, Gesé, Genís Valentín, Kellner, Nikola, Hurt, Ed, Sinning, Irmgard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191838/ https://www.ncbi.nlm.nih.gov/pubmed/37081320 http://dx.doi.org/10.1038/s41594-023-00973-1 |
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