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Dynamic epistasis analysis reveals how chromatin remodeling regulates transcriptional bursting

Transcriptional bursting has been linked to the stochastic positioning of nucleosomes. However, how bursting is regulated by the remodeling of promoter nucleosomes is unknown. Here, we use single-molecule live-cell imaging of GAL10 transcription in Saccharomyces cerevisiae to measure how bursting ch...

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Detalles Bibliográficos
Autores principales:	Brouwer, Ineke, Kerklingh, Emma, van Leeuwen, Fred, Lenstra, Tineke L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191856/ https://www.ncbi.nlm.nih.gov/pubmed/37127821 http://dx.doi.org/10.1038/s41594-023-00981-1

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