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Libman-Sacks Endocarditis With Triple Valvular Involvement

Systemic lupus erythematosus (SLE) is a systemic inflammatory autoimmune disease with a broad spectrum of clinical manifestations. Libman-Sacks endocarditis (LSE) is due to sterile vegetations that arise in association with SLE. Nonbacterial thrombotic endocarditis, also known as marantic endocardit...

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Autores principales: Asher Syed, Meeran, Khokhar, Muhammad Usama, Akbar, Farhan, Asfand, Muhammad, Shakoor, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191869/
https://www.ncbi.nlm.nih.gov/pubmed/37214052
http://dx.doi.org/10.7759/cureus.37734
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author Asher Syed, Meeran
Khokhar, Muhammad Usama
Akbar, Farhan
Asfand, Muhammad
Shakoor, Hassan
author_facet Asher Syed, Meeran
Khokhar, Muhammad Usama
Akbar, Farhan
Asfand, Muhammad
Shakoor, Hassan
author_sort Asher Syed, Meeran
collection PubMed
description Systemic lupus erythematosus (SLE) is a systemic inflammatory autoimmune disease with a broad spectrum of clinical manifestations. Libman-Sacks endocarditis (LSE) is due to sterile vegetations that arise in association with SLE. Nonbacterial thrombotic endocarditis, also known as marantic endocarditis, Libman-Sacks endocarditis, and verrucous endocarditis, is linked to a number of illnesses, the most prevalent of which is advanced cancer. Most often, the surfaces of mitral and aortic valves are involved. However, the involvement of the tricuspid valve is possible and is rarely described in the literature. We present a case of a 25-year-old female who presented with LSE, lupus nephritis, and pulmonary involvement secondary to SLE. On detailed exploration, she was found to have SLE with lupus nephritis and pulmonary hypertension secondary to valvular involvement. Through this case, we would like to elaborate on the course of SLE with triple valvular involvement.
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spelling pubmed-101918692023-05-19 Libman-Sacks Endocarditis With Triple Valvular Involvement Asher Syed, Meeran Khokhar, Muhammad Usama Akbar, Farhan Asfand, Muhammad Shakoor, Hassan Cureus Internal Medicine Systemic lupus erythematosus (SLE) is a systemic inflammatory autoimmune disease with a broad spectrum of clinical manifestations. Libman-Sacks endocarditis (LSE) is due to sterile vegetations that arise in association with SLE. Nonbacterial thrombotic endocarditis, also known as marantic endocarditis, Libman-Sacks endocarditis, and verrucous endocarditis, is linked to a number of illnesses, the most prevalent of which is advanced cancer. Most often, the surfaces of mitral and aortic valves are involved. However, the involvement of the tricuspid valve is possible and is rarely described in the literature. We present a case of a 25-year-old female who presented with LSE, lupus nephritis, and pulmonary involvement secondary to SLE. On detailed exploration, she was found to have SLE with lupus nephritis and pulmonary hypertension secondary to valvular involvement. Through this case, we would like to elaborate on the course of SLE with triple valvular involvement. Cureus 2023-04-17 /pmc/articles/PMC10191869/ /pubmed/37214052 http://dx.doi.org/10.7759/cureus.37734 Text en Copyright © 2023, Asher Syed et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Asher Syed, Meeran
Khokhar, Muhammad Usama
Akbar, Farhan
Asfand, Muhammad
Shakoor, Hassan
Libman-Sacks Endocarditis With Triple Valvular Involvement
title Libman-Sacks Endocarditis With Triple Valvular Involvement
title_full Libman-Sacks Endocarditis With Triple Valvular Involvement
title_fullStr Libman-Sacks Endocarditis With Triple Valvular Involvement
title_full_unstemmed Libman-Sacks Endocarditis With Triple Valvular Involvement
title_short Libman-Sacks Endocarditis With Triple Valvular Involvement
title_sort libman-sacks endocarditis with triple valvular involvement
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191869/
https://www.ncbi.nlm.nih.gov/pubmed/37214052
http://dx.doi.org/10.7759/cureus.37734
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