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Libman-Sacks Endocarditis With Triple Valvular Involvement
Systemic lupus erythematosus (SLE) is a systemic inflammatory autoimmune disease with a broad spectrum of clinical manifestations. Libman-Sacks endocarditis (LSE) is due to sterile vegetations that arise in association with SLE. Nonbacterial thrombotic endocarditis, also known as marantic endocardit...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191869/ https://www.ncbi.nlm.nih.gov/pubmed/37214052 http://dx.doi.org/10.7759/cureus.37734 |
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author | Asher Syed, Meeran Khokhar, Muhammad Usama Akbar, Farhan Asfand, Muhammad Shakoor, Hassan |
author_facet | Asher Syed, Meeran Khokhar, Muhammad Usama Akbar, Farhan Asfand, Muhammad Shakoor, Hassan |
author_sort | Asher Syed, Meeran |
collection | PubMed |
description | Systemic lupus erythematosus (SLE) is a systemic inflammatory autoimmune disease with a broad spectrum of clinical manifestations. Libman-Sacks endocarditis (LSE) is due to sterile vegetations that arise in association with SLE. Nonbacterial thrombotic endocarditis, also known as marantic endocarditis, Libman-Sacks endocarditis, and verrucous endocarditis, is linked to a number of illnesses, the most prevalent of which is advanced cancer. Most often, the surfaces of mitral and aortic valves are involved. However, the involvement of the tricuspid valve is possible and is rarely described in the literature. We present a case of a 25-year-old female who presented with LSE, lupus nephritis, and pulmonary involvement secondary to SLE. On detailed exploration, she was found to have SLE with lupus nephritis and pulmonary hypertension secondary to valvular involvement. Through this case, we would like to elaborate on the course of SLE with triple valvular involvement. |
format | Online Article Text |
id | pubmed-10191869 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-101918692023-05-19 Libman-Sacks Endocarditis With Triple Valvular Involvement Asher Syed, Meeran Khokhar, Muhammad Usama Akbar, Farhan Asfand, Muhammad Shakoor, Hassan Cureus Internal Medicine Systemic lupus erythematosus (SLE) is a systemic inflammatory autoimmune disease with a broad spectrum of clinical manifestations. Libman-Sacks endocarditis (LSE) is due to sterile vegetations that arise in association with SLE. Nonbacterial thrombotic endocarditis, also known as marantic endocarditis, Libman-Sacks endocarditis, and verrucous endocarditis, is linked to a number of illnesses, the most prevalent of which is advanced cancer. Most often, the surfaces of mitral and aortic valves are involved. However, the involvement of the tricuspid valve is possible and is rarely described in the literature. We present a case of a 25-year-old female who presented with LSE, lupus nephritis, and pulmonary involvement secondary to SLE. On detailed exploration, she was found to have SLE with lupus nephritis and pulmonary hypertension secondary to valvular involvement. Through this case, we would like to elaborate on the course of SLE with triple valvular involvement. Cureus 2023-04-17 /pmc/articles/PMC10191869/ /pubmed/37214052 http://dx.doi.org/10.7759/cureus.37734 Text en Copyright © 2023, Asher Syed et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Asher Syed, Meeran Khokhar, Muhammad Usama Akbar, Farhan Asfand, Muhammad Shakoor, Hassan Libman-Sacks Endocarditis With Triple Valvular Involvement |
title | Libman-Sacks Endocarditis With Triple Valvular Involvement |
title_full | Libman-Sacks Endocarditis With Triple Valvular Involvement |
title_fullStr | Libman-Sacks Endocarditis With Triple Valvular Involvement |
title_full_unstemmed | Libman-Sacks Endocarditis With Triple Valvular Involvement |
title_short | Libman-Sacks Endocarditis With Triple Valvular Involvement |
title_sort | libman-sacks endocarditis with triple valvular involvement |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191869/ https://www.ncbi.nlm.nih.gov/pubmed/37214052 http://dx.doi.org/10.7759/cureus.37734 |
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