Nuclear softening mediated by Sun2 suppression delays mechanical stress-induced cellular senescence

Nuclear decoupling and softening are the main cellular mechanisms to resist mechanical stress-induced nuclear/DNA damage, however, its molecular mechanisms remain much unknown. Our recent study of Hutchinson-Gilford progeria syndrome (HGPS) disease revealed the role of nuclear membrane protein Sun2...

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Detalles Bibliográficos
Autores principales: Yue, Xianlin, Cui, Jie, Sun, Zewei, Liu, Lei, Li, Ying, Shao, Liwei, Feng, Qi, Wang, Ziyue, Hambright, William S., Cui, Yan, Huard, Johnny, Mu, Yanling, Mu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192198/
https://www.ncbi.nlm.nih.gov/pubmed/37198162
http://dx.doi.org/10.1038/s41420-023-01467-1

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