Cargando…

The cancer-testis lncRNA LINC01977 promotes HCC progression by interacting with RBM39 to prevent Notch2 ubiquitination

Cancer-testis genes are involved in the occurrence and development of cancer, but the role of cancer-testis-associated lncRNAs (CT-lncRNAs) in hepatocellular carcinoma (HCC) remains to be explored. Here, we discovered a novel CT-lncRNA, LINC01977, based on the Genotype-Tissue Expression (GTEx) and T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xia, Anliang, Yue, Qi, Zhu, Mingming, Xu, Jianbo, Liu, Siyuan, Wu, Yue, Wang, Zhangding, Xu, Zhu, An, Hongda, Wang, Qiang, Wang, Shouyu, Sun, Beicheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192213/ https://www.ncbi.nlm.nih.gov/pubmed/37198207 http://dx.doi.org/10.1038/s41420-023-01459-1

Ejemplares similares

LINC01977 Promotes Breast Cancer Progression and Chemoresistance to Doxorubicin by Targeting miR-212-3p/GOLM1 Axis
por: Li, Zheng, et al.
Publicado: (2021)

Super-enhancer hijacking LINC01977 promotes malignancy of early-stage lung adenocarcinoma addicted to the canonical TGF-β/SMAD3 pathway
por: Zhang, Te, et al.
Publicado: (2022)

Prognostic and predictive role of a metabolic rate‐limiting enzyme signature in hepatocellular carcinoma
por: Wang, Zhangding, et al.
Publicado: (2021)

The mechanism of LncRNA01977 in lung adenocarcinoma through the SDF-1/CXCR4 pathway
por: Lai, Xiao-Rong, et al.
Publicado: (2022)

APAF1‐Binding Long Noncoding RNA Promotes Tumor Growth and Multidrug Resistance in Gastric Cancer by Blocking Apoptosome Assembly
por: Wang, Qiang, et al.
Publicado: (2022)

Arginine reprograms metabolism in liver cancer via RBM39
por: Mossmann, Dirk, et al.
Publicado: (2023)

Systematic pan‐cancer analysis identifies RBM39 as an immunological and prognostic biomarker
por: Zhang, Rui, et al.
Publicado: (2022)

RBM39 Alters Phosphorylation of c-Jun and Binds to Viral RNA to Promote PRRSV Proliferation
por: Song, Yinna, et al.
Publicado: (2021)

Autoregulation of RBM10 and cross-regulation of RBM10/RBM5 via alternative splicing-coupled nonsense-mediated decay
por: Sun, Yue, et al.
Publicado: (2017)

Emerging role of RNA methyltransferase METTL3 in gastrointestinal cancer
por: Wang, Qiang, et al.
Publicado: (2020)

Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15
por: Faust, Tyler, et al.
Publicado: (2019)

Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39
por: Campagne, Sébastien, et al.
Publicado: (2023)

Targeting the spliceosome through RBM39 degradation results in exceptional responses in high-risk neuroblastoma models
por: Singh, Shivendra, et al.
Publicado: (2021)

Hypoxia-induced long non-coding RNA DARS-AS1 regulates RBM39 stability to promote myeloma malignancy
por: Tong, Jia, et al.
Publicado: (2020)

SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis
por: Zhu, Tingting, et al.
Publicado: (2021)

Alternative Splicing of Cdh23 Exon 68 Is Regulated by RBM24, RBM38, and PTBP1
por: Li, Nana, et al.
Publicado: (2020)

Linc-KILH potentiates Notch1 signaling through inhibiting KRT19 phosphorylation and promotes the malignancy of hepatocellular carcinoma
por: Zhang, Xudong, et al.
Publicado: (2021)

m(6)A Reader HNRNPA2B1 Promotes Esophageal Cancer Progression via Up-Regulation of ACLY and ACC1
por: Guo, Huimin, et al.
Publicado: (2020)

Rbm24a and Rbm24b Are Required for Normal Somitogenesis
por: Maragh, Samantha, et al.
Publicado: (2014)

RBM6-RBM5 transcription-induced chimeras are differentially expressed in tumours
por: Wang, Ke, et al.
Publicado: (2007)

Negative autoregulation of BMP dependent transcription by SIN3B splicing reveals a role for RBM39
por: Faherty, Noel, et al.
Publicado: (2016)

Overlaid Transcriptional and Proteome Analyses Identify Mitotic Kinesins as Important Targets of Arylsulfonamide-Mediated RBM39 Degradation
por: Coomar, Seemon, et al.
Publicado: (2023)

Splicing Factor RBM20 Regulates Transcriptional Network of Titin Associated and Calcium Handling Genes in The Heart
por: Guo, Wei, et al.
Publicado: (2018)

iPSC Modeling of RBM20-Deficient DCM Identifies Upregulation of RBM20 as a Therapeutic Strategy
por: Briganti, Francesca, et al.
Publicado: (2020)

Targeting KRAS4A splicing through the RBM39/DCAF15 pathway inhibits cancer stem cells
por: Chen, Wei-Ching, et al.
Publicado: (2021)

The transcription factor c-Jun inhibits RBM39 to reprogram pre-mRNA splicing during genotoxic stress
por: Lemaitre, Florence, et al.
Publicado: (2022)

LINC01468 drives NAFLD-HCC progression through CUL4A-linked degradation of SHIP2
por: Wang, Hongquan, et al.
Publicado: (2022)

Sagittal spino-pelvic parameters of adult isthmic spondylolisthesis
por: Zhu, Feng, et al.
Publicado: (2015)

Regulation of zebrafish dorsoventral patterning by phase separation of RNA-binding protein Rbm14
por: Xiao, Yue, et al.
Publicado: (2019)

Muscle-Specific Mis-Splicing and Heart Disease Exemplified by RBM20
por: Rexiati, Maimaiti, et al.
Publicado: (2018)

Oncogenic action of the exosome cofactor RBM7 by stabilization of CDK1 mRNA in breast cancer
por: Xi, Pei-Wen, et al.
Publicado: (2020)

Prognostic value of decreased expression of RBM4 in human gastric cancer
por: Yong, Hongmei, et al.
Publicado: (2016)

An NAD(+)-Dependent Deacetylase SIRT7 Promotes HCC Development Through Deacetylation of USP39
por: Dong, Ling, et al.
Publicado: (2020)

High-affinity neoantigens correlate with better prognosis and trigger potent antihepatocellular carcinoma (HCC) activity by activating CD39(+)CD8(+) T cells
por: Liu, Ting, et al.
Publicado: (2021)

Loss of the RNA-binding protein Rbm15 disrupts liver maturation in zebrafish
por: Hu, Liang, et al.
Publicado: (2020)

RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis
por: Zhang, Yanghai, et al.
Publicado: (2022)

Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types
por: Wang, Cheng, et al.
Publicado: (2016)

RBM25 Mediates Abiotic Responses in Plants
por: Cheng, Chunhong, et al.
Publicado: (2017)

Rbm24 modulates adult skeletal muscle regeneration via regulation of alternative splicing
por: Zhang, Mengkai, et al.
Publicado: (2020)

Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis
por: Zou, Qianxing, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2tn1g088n726kdas2bj85j8su9