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Quality control of protein synthesis in the early elongation stage

In the early stage of bacterial translation, peptidyl-tRNAs frequently dissociate from the ribosome (pep-tRNA drop-off) and are recycled by peptidyl-tRNA hydrolase. Here, we establish a highly sensitive method for profiling of pep-tRNAs using mass spectrometry, and successfully detect a large number...

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Detalles Bibliográficos
Autores principales: Nagao, Asuteka, Nakanishi, Yui, Yamaguchi, Yutaro, Mishina, Yoshifumi, Karoji, Minami, Toya, Takafumi, Fujita, Tomoya, Iwasaki, Shintaro, Miyauchi, Kenjyo, Sakaguchi, Yuriko, Suzuki, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192219/
https://www.ncbi.nlm.nih.gov/pubmed/37198183
http://dx.doi.org/10.1038/s41467-023-38077-5