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Forward genetic screening using fundus spot scale identifies an essential role for Lipe in murine retinal homeostasis
Microglia play a role in the pathogenesis of many retinal diseases. Fundus spots in mice often correlate with the accumulation of activated subretinal microglia. Here we use a semiquantitative fundus spot scoring scale in combination with an unbiased, state-of-the-science forward genetics pipeline t...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192353/ https://www.ncbi.nlm.nih.gov/pubmed/37198396 http://dx.doi.org/10.1038/s42003-023-04870-7 |