Cell activation-based screening of natively paired human T cell receptor repertoires

Adoptive immune therapies based on the transfer of antigen-specific T cells have been used successfully to treat various cancers and viral infections, but improved techniques are needed to identify optimally protective human T cell receptors (TCRs). Here we present a high-throughput approach to the...

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Detalles Bibliográficos
Autores principales: Fahad, Ahmed S., Chung, Cheng Yu, López Acevedo, Sheila N., Boyle, Nicoleen, Madan, Bharat, Gutiérrez-González, Matías F., Matus-Nicodemos, Rodrigo, Laflin, Amy D., Ladi, Rukmini R., Zhou, John, Wolfe, Jacy, Llewellyn-Lacey, Sian, Koup, Richard A., Douek, Daniel C., Balfour, Henry H., Price, David A., DeKosky, Brandon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192375/
https://www.ncbi.nlm.nih.gov/pubmed/37198258
http://dx.doi.org/10.1038/s41598-023-31858-4

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