Liver-specific overexpression of HKDC1 increases hepatocyte size and proliferative capacity

A primary role of the liver is to regulate whole body glucose homeostasis. Glucokinase (GCK) is the main hexokinase (HK) expressed in hepatocytes and functions to phosphorylate the glucose that enters via GLUT transporters to become glucose-6-phosphate (G6P), which subsequently commits glucose to en...

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Detalles Bibliográficos
Autores principales: Pusec, Carolina M., Ilievski, Vladimir, De Jesus, Adam, Farooq, Zeenat, Zapater, Joseph L., Sweis, Nadia, Ismail, Hagar, Khan, Md Wasim, Ardehali, Hossein, Cordoba-Chacon, Jose, Layden, Brian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192376/
https://www.ncbi.nlm.nih.gov/pubmed/37198225
http://dx.doi.org/10.1038/s41598-023-33924-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192376/
https://www.ncbi.nlm.nih.gov/pubmed/37198225
http://dx.doi.org/10.1038/s41598-023-33924-3

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