Cargando…
DARPins bind their cytosolic targets after having been translocated through the protective antigen pore of anthrax toxin
Intracellular protein–protein interactions in aberrant signaling pathways have emerged as a prime target in several diseases, particularly cancer. Since many protein–protein interactions are mediated by rather flat surfaces, they can typically not be interrupted by small molecules as they require ca...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192448/ https://www.ncbi.nlm.nih.gov/pubmed/37198284 http://dx.doi.org/10.1038/s41598-023-34647-1 |