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A novel IRE1 kinase inhibitor for adjuvant glioblastoma treatment

Inositol-requiring enzyme 1 (IRE1) is a major mediator of the unfolded protein response (UPR), which is activated upon endoplasmic reticulum (ER) stress. Tumor cells experience ER stress due to adverse microenvironmental cues, a stress overcome by relying on IRE1 signaling as an adaptive mechanism....

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Detalles Bibliográficos
Autores principales:	Pelizzari-Raymundo, Diana, Doultsinos, Dimitrios, Pineau, Raphael, Sauzay, Chloé, Koutsandreas, Thodoris, Langlais, Timothy, Carlesso, Antonio, Gkotsi, Elena, Negroni, Luc, Avril, Tony, Chatziioannou, Aristotelis, Chevet, Eric, Eriksson, Leif A., Guillory, Xavier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192531/ https://www.ncbi.nlm.nih.gov/pubmed/37216120 http://dx.doi.org/10.1016/j.isci.2023.106687

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