Cargando…

Studies on the inhibitory effect of isavuconazole on flumatinib metabolism in vitro and in vivo

As the validated agent for the treatment of chronic myelogenous leukemia (CML), flumatinib is a novel oral tyrosine kinase inhibitor (TKI) with higher potency and selectivity for BCR-ABL1 kinase compared to imatinib. Many patients experience aspergillosis infection and they may start using isavucona...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Ya-nan, Xu, Xinhao, Nie, Jingjing, Hu, Yingying, Xu, Xuegu, Xu, Ren-ai, Du, Xiaoxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192561/ https://www.ncbi.nlm.nih.gov/pubmed/37214442 http://dx.doi.org/10.3389/fphar.2023.1168852

Ejemplares similares

Basic and clinical study of efficacy and adverse effects of flumatinib in Ph(+) ALL
por: Wang, Jun, et al.
Publicado: (2023)

Inhibitory mechanism of vortioxetine on CYP450 enzymes in human and rat liver microsomes
por: Zhan, Yunyun, et al.
Publicado: (2023)

Evaluation of the inhibitory effect of quercetin on the pharmacokinetics of tucatinib in rats by a novel UPLC–MS/MS assay
por: Zhang, Ying, et al.
Publicado: (2022)

A Novel UPLC-MS/MS Assay for the Measurement of Linezolid and its Metabolite PNU-142300 in Human Serum and its Application to Patients With Renal Insufficiency
por: Wang, Yingying, et al.
Publicado: (2021)

No Dose Adjustment for Isavuconazole Based on Age or Sex
por: Desai, Amit V., et al.
Publicado: (2019)

Bronchopulmonary penetration of isavuconazole in lung transplant recipients
por: Caballero-Bermejo, Antonio F., et al.
Publicado: (2023)

Pharmacodynamics of Isavuconazole in a Rabbit Model of Cryptococcal Meningoencephalitis
por: Kovanda, Laura L., et al.
Publicado: (2019)

Impact of Mucositis on Absorption and Systemic Drug Exposure of Isavuconazole
por: Kovanda, Laura L., et al.
Publicado: (2017)

Population Pharmacokinetics of Isavuconazole in Subjects with Mild or Moderate Hepatic Impairment
por: Desai, Amit, et al.
Publicado: (2016)

Inhibitory effect of celecoxib on agomelatine metabolism in vitro and in vivo
por: He, Jiayang, et al.
Publicado: (2018)

Effect of high-fat diet on the pharmacokinetics and safety of flumatinib in healthy Chinese subjects
por: Kuang, Yun, et al.
Publicado: (2020)

Inhibitory Effect of Imperatorin on the Pharmacokinetics of Diazepam In Vitro and In Vivo
por: Zhou, Yunfang, et al.
Publicado: (2020)

Efficacy and Associated Drug Exposures of Isavuconazole and Fluconazole in an Experimental Model of Coccidioidomycosis
por: Kovanda, Laura L., et al.
Publicado: (2021)

The Effect of Posaconazole and Isavuconazole on the Pharmacokinetics of Erdafitinib in Beagle Dogs by UPLC-MS/MS
por: Ruan, Lan-hong, et al.
Publicado: (2021)

QT Interval Shortening With Isavuconazole: In Vitro and In Vivo Effects on Cardiac Repolarization
por: Keirns, J, et al.
Publicado: (2017)

Inhibitory Effect of Kurarinone on Growth of Human Non-small Cell Lung Cancer: An Experimental Study Both in Vitro and in Vivo Studies
por: Yang, Jie, et al.
Publicado: (2018)

Tissue Distribution and Elimination of Isavuconazole following Single and Repeat Oral-Dose Administration of Isavuconazonium Sulfate to Rats
por: Schmitt-Hoffmann, Anne-Hortense, et al.
Publicado: (2017)

Development of a UPLC-MS/MS method for the determination of orelabrutinib in rat plasma and its application in pharmacokinetics
por: Liu, Ya-nan, et al.
Publicado: (2022)

Pharmacokinetics of single- and multiple-dose flumatinib in patients with chronic phase chronic myeloid leukemia
por: Jiang, Bo, et al.
Publicado: (2023)

Flumatinib, a selective inhibitor of BCR-ABL/PDGFR/KIT, effectively overcomes drug resistance of certain KIT mutants
por: Zhao, Jie, et al.
Publicado: (2014)

Tissue Distribution and Penetration of Isavuconazole at the Site of Infection in Experimental Invasive Aspergillosis in Mice with Underlying Chronic Granulomatous Disease
por: Lee, Annie, et al.
Publicado: (2019)

Evaluation of commonly used cardiovascular drugs in inhibiting vonoprazan metabolism in vitro and in vivo
por: Wang, Yiran, et al.
Publicado: (2022)

UPLC-MS/MS Technology for the Quantitative Methodology and Pharmacokinetic Analysis of Voxtalisib in Rat Plasma
por: Li, Qingqing, et al.
Publicado: (2022)

Isavuconazole Population Pharmacokinetic Analysis Using Nonparametric Estimation in Patients with Invasive Fungal Disease (Results from the VITAL Study)
por: Kovanda, Laura L., et al.
Publicado: (2016)

Identification of a novel pyridine derivative with inhibitory activity against ovarian cancer progression in vivo and in vitro
por: Si, Lulu, et al.
Publicado: (2022)

Ascorbic Acid Inhibits Liver Cancer Growth and Metastasis in vitro and in vivo, Independent of Stemness Gene Regulation
por: Wan, Jingjing, et al.
Publicado: (2021)

Preparation of a Sunitinib loaded microemulsion for ocular delivery and evaluation for the treatment of corneal neovascularization in vitro and in vivo
por: Shi, Jieran, et al.
Publicado: (2023)

Propofol inhibits neuroinflammation and metabolic reprogramming in microglia in vitro and in vivo
por: Guan, Shuyuan, et al.
Publicado: (2023)

AK2 Promotes the Migration and Invasion of Lung Adenocarcinoma by Activating TGF-β/Smad Pathway In vitro and In vivo
por: Cai, Fangfang, et al.
Publicado: (2021)

Farrerol prevents Angiotensin II-induced cardiac remodeling in vivo and in vitro
por: He, Jian, et al.
Publicado: (2023)

Flumatinib plus venetoclax as an effective therapy for Philadelphia chromosome‐positive acute myeloid leukemia: A case report
por: Huang, Si‐Man, et al.
Publicado: (2023)

Effects of bergapten on the pharmacokinetics of macitentan in rats both in vitro and in vivo
por: Xu, Jia, et al.
Publicado: (2023)

Targeting Mouse Double Minute 2: Current Concepts in DNA Damage Repair and Therapeutic Approaches in Cancer
por: Li, Wen, et al.
Publicado: (2020)

In vitro synergy of isavuconazole in combination with colistin against Candida auris
por: Schwarz, Patrick, et al.
Publicado: (2020)

In Vitro Synergistic Interactions of Isavuconazole and Echinocandins against Candida auris
por: Caballero, Unai, et al.
Publicado: (2021)

Synergistic In Vitro Interaction of Isavuconazole and Isoquercitrin against Candida glabrata
por: Schwarz, Petra V., et al.
Publicado: (2022)

In Vitro Activity of Isavuconazole and Amphotericin B in Association against Mucorales
por: Ortalli, Gaia, et al.
Publicado: (2023)

PB1749: APOPTOTIC EFFECT OF FLUMATINIB COMBINED WITH BCL2 INHIBITOR ON PH+ B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
por: Gu, Y., et al.
Publicado: (2022)

Skimmin Improves Insulin Resistance via Regulating the Metabolism of Glucose: In Vitro and In Vivo Models
por: Zhang, Guoqiang, et al.
Publicado: (2020)

In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues
por: Uche, Fidelia Ijeoma, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2fr4j1krtba7eudcehebcq0duj